From:Multiplicity of cerebrospinal fluid functions: New challenges in health and disease
Rat Aging* |
Human Disease† |
|||||
---|---|---|---|---|---|---|
3 mo |
19 mo |
30 mo |
Normal |
NPH |
AD |
|
CSF Formation Rate (ml/min) |
0.00121 |
0.00148 |
0.00065 |
0.40 |
0.25 |
0.20 |
CSF Volume (space) (ml) |
0.156 |
0.196 |
0.308 |
150 |
300 |
250 |
CSF Turnover Rate (volumes/day) |
11 |
10.8 |
3.0 |
4 |
1.2 |
1.2 |