Capillary |
Parenchyma |
|||||||
---|---|---|---|---|---|---|---|---|
11 donors including CAA (ADNC +/CAA + & ADNC −/CAA −) |
10 donors including AD (ADNC +/CAA- & ADNC −/CAA −) |
11 donors including CAA (ADNC +/CAA + & ADNC − −/CAA −) |
10 donors including AD (ADNC +/CAA − & ADNC −/CAA −) |
|||||
ρ |
p |
ρ |
p |
ρ |
p |
ρ |
p |
|
Aβ |
1.00 |
– |
1.00 |
– |
1.00 |
– |
1.00 |
– |
ECM related protein |
||||||||
COL6A1 |
0.855 |
8.07E−04** |
0.467 |
1.74E−01 |
0.273 |
4.17E−01 |
0.309 |
3.85E−01 |
FBN1 |
0.800 |
3.11E−03** |
0.515 |
1.28E−01 |
− 0.0636 |
8.53E−01 |
0.527 |
1.17E−01 |
COL6A2 |
0.782 |
4.47E−03** |
0.370 |
2.93E−01 |
− 0.0909 |
7.90E−01 |
0.406 |
2.44E−01 |
COL6A3 |
0.691 |
1.86E−02* |
0.297 |
4.05E−01 |
− 0.100 |
7.70E−01 |
0.261 |
4.67E−01 |
Cell adhesion related protein |
||||||||
CD44 |
0.645 |
3.20E−02* |
0.661 |
3.76E−02* |
0.327 |
3.26E−01 |
0.539 |
1.08E−01 |
HEPACAM |
0.618 |
4.26E−02* |
0.418 |
2.29E−01 |
− 0.536 |
8.90E−02 |
0.333 |
3.47E−01 |
PCBP1 |
− 0.809 |
2.56E−03** |
− 0.624 |
5.37E−02 |
− 0.264 |
4.33E−01 |
0.612 |
6.00E−02 |
Fibrosis related protein |
||||||||
HSP90A |
0.764 |
6.23E−03** |
− 0.0667 |
8.55E−01 |
0.227 |
5.02E−01 |
0.236 |
5.11E−01 |
LDHA |
0.727 |
1.12E−02* |
0.164 |
6.51E−01 |
0.00909 |
9.79E−01 |
0.188 |
6.03E−01 |
S100A6 |
0.664 |
2.60E−02* |
0.115 |
7.51E−01 |
0.264 |
4.33E−01 |
− 0.273 |
4.46E−01 |
PML |
0.636 |
3.53E−02* |
0.527 |
1.17E−01 |
− 0.0818 |
8.11E−01 |
0.273 |
4.46E−01 |
DUSP3 |
− 0.782 |
4.47E−03** |
− 0.139 |
7.01E−01 |
− 0.445 |
1.70E−01 |
0.103 |
7.77E−01 |
ROS related protein |
||||||||
APOE |
0.827 |
1.68E−03** |
0.321 |
3.65E−01 |
0.582 |
6.04E−02 |
0.467 |
1.74E−01 |
GNG12 |
0.700 |
1.65E−02* |
0.673 |
3.30E−02* |
− 0.00909 |
9.79E−01 |
0.382 |
2.76E−01 |
GSTO1 |
0.673 |
2.33E−02* |
− 0.0545 |
8.81E−01 |
0.191 |
5.74E−01 |
− 0.273 |
4.46E−01 |
IGHG1 |
0.655 |
2.89 e−02 * |
0.309 |
3.85E−01 |
0.0818 |
8.11E−01 |
0.370 |
2.93E−01 |
Antioxidant related protein |
||||||||
GFAP |
0.864 |
6.12E−04** |
0.200 |
5.80E−01 |
0.509 |
1.10E−01 |
− 0.224 |
5.33E−01 |
PRDX2 |
0.727 |
1.12E−02* |
0.139 |
7.01E−01 |
− 0.182 |
5.93E−01 |
− 0.224 |
5.33E−01 |
CYB5R3 |
0.655 |
2.89 e−02 * |
0.527 |
1.17E−01 |
− 0.136 |
6.89E−01 |
0.164 |
6.51E−01 |
CLU |
0.655 |
2.89 e−02 * |
0.176 |
6.27E−01 |
0.509 |
1.10E−01 |
− 0.0303 |
9.34E−01 |
PRDX6 |
0.627 |
3.88E−02* |
− 0.236 |
5.11E−01 |
0.218 |
5.19E−01 |
− 0.0182 |
9.60E−01 |
Akt related protein |
||||||||
PDHX |
− 0.791 |
3.75E−03** |
− 0.127 |
7.26E−01 |
− 0.0818 |
8.11E−01 |
0.309 |
3.85E−01 |
NCSTN |
− 0.782 |
4.47E−03** |
− 0.285 |
4.25E−01 |
− 0.0182 |
9.58E−01 |
− 0.00606 |
9.87E−01 |
TPD52L2 |
− 0.691 |
1.86E−02* |
− 0.333 |
3.47E−01 |
− 0.0818 |
8.11E−01 |
− 0.0909 |
8.03E−01 |
PSMC2 |
− 0.664 |
2.60E−02* |
− 0.370 |
2.93E−01 |
0.0182 |
9.58E−01 |
− 0.297 |
4.05E−01 |
Caspase related protein |
||||||||
HEBP1 |
0.691 |
1.86E−02* |
0.697 |
2.51E−02* |
− 0.455 |
1.60E−01 |
0.0788 |
8.29E−01 |
CA1 |
0.645 |
3.20E−02* |
0.139 |
7.01E−01 |
− 0.0455 |
8.94E−01 |
0.345 |
3.28E−01 |
TUBB2B |
− 0.845 |
1.05E−03** |
− 0.345 |
3.28E−01 |
0.109 |
7.50E−01 |
0.418 |
2.29E−01 |
ACOX1 |
− 0.882 |
3.30E−04** |
− 0.770 |
9.22E−03** |
− 0.327 |
3.26E−01 |
− 0.285 |
4.25E−01 |
ATP2A2 |
− 0.873 |
4.55E−04** |
− 0.382 |
2.76E−01 |
− 0.409 |
2.12E−01 |
0.333 |
3.47E−01 |
PTGES3 |
− 0.736 |
9.76E−03** |
− 0.00606 |
9.87E−01 |
− 0.364 |
2.72E−01 |
0.455 |
1.87E−01 |
PRKAR2B |
− 0.736 |
9.76E−03** |
− 0.455 |
1.87E−01 |
0 |
– |
0.273 |
4.46E−01 |
TUBB4A |
− 0.718 |
1.28E−02* |
−0.200 |
5.80E−01 |
− 0.309 |
3.55E−01 |
0.442 |
2.00E−01 |
PPP2R2A |
− 0.691 |
1.86E−02* |
− 0.00606 |
9.87E−01 |
− 0.245 |
4.67E−01 |
0.358 |
3.10E−01 |
TUBB6 |
− 0.664 |
2.60E−02* |
− 0.382 |
2.76E−01 |
0.145 |
6.70E−01 |
0.152 |
6.76E−01 |
Others |
||||||||
KANK2 |
0.773 |
5.30E−03** |
0.0909 |
8.03E−01 |
0.618 |
4.26E−02* |
− 0.0788 |
8.29E−01 |
var |
− 0.945 |
1.12E−05** |
− 0.661 |
3.76E−02* |
− 0.364 |
2.72E−01 |
− 0.0303 |
9.34E−01 |
ACTN2 |
− 0.818 |
2.08E−03** |
− 0.479 |
1.62E−01 |
− 0.218 |
5.19E−01 |
0.0788 |
8.29E−01 |
EXOC6B |
− 0.800 |
3.11E−03** |
− 0.188 |
6.03E−01 |
− 0.327 |
3.26E−01 |
− 0.176 |
6.27E−01 |
HSPH1 |
− 0.709 |
1.46E−02* |
− 0.261 |
4.67E−01 |
− 0.227 |
5.02E−01 |
− 0.0303 |
9.34E−01 |
SV2B |
− 0.709 |
1.46E−02* |
− 0.382 |
2.76E−01 |
− 0.445 |
1.70E−01 |
0.248 |
4.89E−01 |
ETFA |
− 0.700 |
1.65E−02* |
0.224 |
5.33E−01 |
0.0182 |
9.58E−01 |
0.0182 |
9.60E−01 |
FARSA |
− 0.691 |
1.86E−02* |
− 0.309 |
3.85E−01 |
0 |
– |
− 0.0788 |
8.29E−01 |