Fig. 3 From:Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders Dose linearity of intrathecally administered gadobutrol. Mean individual posterior predicted concentration of gadobutrol following intrathecal administration ofA0.1 mmol,B0.25 mmol andC0.5 mmol of gadobutrol; also shown is theDdose-normalized concentrations, demonstrating dose linearity Back to article page